Bestehende Verfahren zur Behandlung von Psoriasis Patent DEA1 - Composition, useful in the treatment of psoriasis, comprises e.g., Gan Jiang - Google Patents Bestehende Verfahren zur Behandlung von Psoriasis Patent DET2 - Zubereitungen und verfahren für die behandlung von krebs und - Google Patents


Bestehende Verfahren zur Behandlung von Psoriasis

Try the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents. Vakzin-Zusammensetzung, die die folgenden Bestandteile umfasst: A vaccine composition comprising the following components: The composition of claim 1, wherein the carrier is a liposome. The composition of claim 1 or 2, wherein the carrier is a Bestehende Verfahren zur Behandlung von Psoriasis vesicle.

A composition according to any one of claims 1 Bestehende Verfahren zur Behandlung von Psoriasis 3, further comprising an adjuvant. The composition of claim 4, wherein the adjuvant is selected from the group consisting of lipophilic muramyl dipeptide derivatives, nonionic block polymers, aluminum hydroxide, aluminum phosphate and lipid A is selected. Zusammensetzung nach Anspruch 5, wobei das Adjuvans Lipid A ist. The composition of claim 5, wherein the adjuvant is lipid A. A composition according to any one of claims 1 to 6, further comprising a growth factor bound to the immunizing unit.

A composition according to any of claimsfurther comprising a growth factor bound to the hydrophobic moiety. A composition according to claim 8, wherein the hydrophobic moiety comprises at least one long chain fatty acid having at least 10 carbon atoms Bestehende Verfahren zur Behandlung von Psoriasis the lipid backbone.

Bestehende Verfahren zur Behandlung von Psoriasis composition of claim 9, wherein the hydrophobic moiety is selected from the group consisting of http://julia-kuhn.de/ciclosporin-psoriasis.php acid, stearic acid, myristic acid, lauric acid, oleic acid, linoleic acid and linolenic acid. The composition of claim 10, wherein the hydrophobic moiety is palmitic acid. Use of a composition according to any one of claims 1 to 11 for the manufacture of a vaccine for preventing or reducing cancer in a human or animal.

Composition according to Medikamente für Gelenke bei Psoriasis of claims 1 to 11 for use in medicine. Die vorliegende Erfindung betrifft Vakzine zur Vorbeugung oder Linderung von Krebs bei Menschen oder Tieren. The present invention relates to vaccines for the prevention or alleviation of cancer in humans or animals. In particular, the present invention relates to immunogenic compositions comprising growth factors, antibodies specific for growth factors and methods of use thereof.

Bestehende Verfahren zur Behandlung von Psoriasis der Erfindung Background of the Invention. While many cancers are treatable by chemotherapeutic agents, a significant number of cancers is intrinsically drug resistant and others acquire resistance during or following chemotherapy.

Cancer is often resistant to more than one type of drug. This phenomenon is called multidrug resistance or MDR. Consequently, there is Bestehende Verfahren zur Behandlung von Psoriasis great need for compositions and methods that can be used in addition to or as an alternative to chemotherapy for the treatment of cancer.

Ein klinisches Hauptproblem von Krebs ist Metastasierung. A major http://julia-kuhn.de/diaet-hilft-nicht-gegen-schuppenflechte.php problem of cancer metastasis.

At the time, in which the primary tumor is identified and located, seed cells are already escaped to other organs in the body and moved or metastasized, where they establish secondary tumors. Surgical procedures are rarely sufficient to cure cancer, as well as after removal of the primary tumor survive many secondary tumors and proliferate.

Consequently, there is an immediate and emphatic need for methods of extinction of secondary http://julia-kuhn.de/wir-kaempfen-mit-psoriasis.php that already exist. Cancer cells that escape the primary tumor are usually in the venous and lymphatic circulation promoted until they get stuck in a downstream capillary bed or lymph nodes.

However, there is only 1 of 10, cancer cells that escape the primary tumor, survival under Justify a secondary tumor. Successful cancer cells are those for survival and growth find a proper environment. The favorable environment includes hormones and growth-promoting factors. Stimulierende Faktoren beinhalten lokale Wachstumsfaktoren, vom Wirt produzierte Hormone und autostimulierende Wachstumsfaktoren, die von den Tumorzellen selbst produziert werden.

Stimulating factors include local growth factors, hormones produced by the host car and stimulating growth factors produced by the tumor cells themselves. Consequently, there is an immediate Bestehende Verfahren zur Behandlung von Psoriasis for methods and vigorously with which the prevention or inhibition of cancer metastasis and the formation of secondary tumors can be effected.

Ferner bestehen viele andere Hyperproliferations-Krankheiten. There are also many other hyperproliferative diseases. Hyperproliferative diseases are caused by non-cancerous ie, non-neoplastic cells that are produced in response to a particular growth factor.

Examples of such hyperproliferative diseases Bestehende Verfahren zur Behandlung von Psoriasis diabetic retinopathy, psoriasis, endometriosis, suffering from macular degeneration and benign growth disorders such as prostate enlargement and lipomas.

It is known that causes many new cancers by growth factors that affect either the cancer cell itself or normal tissue around the cancer cells and the survival of the cancer cell to facilitate ie, angiogenesis factorsand existing cancers and hyperproliferative diseases are stimulated. Es besteht eine direkte Korrelation zwischen dem Spiegel von bestimmten Wachstumsfaktoren im Kreislauf und Krebsproliferation. There is a direct Seborrhoe von Volksmittel Psoriasis between the eBay Lupus oder Psoriasis his of certain growth factors in the cycle and cancer proliferation.

One potential method for the treatment would be to regulate the level of growth factors in the circulation in a patient in order to prevent tripping or a recurrence of cancer and to alleviate already existing cancers or eliminate. For example, disclosed in WO-A a vaccine composition for the treatment of cancer, the IL-2 or other lymphokine with an ILlike effect that is applied to the surface of a liposome comprises. Thus, the compositions are required to remove the appropriate growth factors from circulation or inhibit the growth-promoting activity of growth factors.

Zusammenfassung der Erfindung Summary of the Invention. Im Allgemeinen beinhaltet die vorliegende Erfindung Verfahren und Zusammensetzungen zur Vorbeugung oder Behandlung von Krebserkrankungen. Generally, the present invention includes methods and compositions for the prevention or treatment of cancer.

Http://julia-kuhn.de/psoriasis-castoreum.php Bestehende Verfahren zur Behandlung von Psoriasis, the present invention involves immunizing a growth factor-containing compositions which elicit the production of specific click at this page for the growth factor when administered to a human or animal.

According to the present invention there is provided a method of vaccinating a human or animal against growth factors that are associated with specific cancer types and hyperproliferative diseases. Bestimmte Krebserkrankungen sind nur mit einem Wachstumsfaktor verbunden und andere Krebserkrankungen werden durch Wachstumsfaktoren gesteuert.

Certain cancers are associated with a growth factor and other cancers are controlled by growth factors. Bestehende Verfahren zur Behandlung von Psoriasis of compositions with a growth factor include liposomes or vesicles, which parts of a growth factor, a growth factor fragments, synthetic peptides of certain epitopes of growth factors, or modified fragments of a growth factor have presented on their outer Juckreiz der Haut starker. The compositions described above are useful as vaccines to induce autoimmunity against growth factors that would otherwise be recognized as "self" by the immune system and do not act naturally immunogenic.

The resulting circulating antibodies bind the growth factor, and thus prevent the initiation of cancer proliferation, reduce existing Exazerbation der Psoriasis Antibiotika or inhibit the spread of cancer. The present invention also includes antibodies specific for growth factors. These antibodies are produced from humans or animals with strong immune systems and purified and injected into humans or animals with weak or malfunctioning immune systems who need such circulating antibodies.

As cancers according to the present invention, either by active immunization of an individual using the immunizing growth factor-containing compositions, or by passive immunization via administering an antibody or group of antibodies is or are Bestehende Verfahren zur Behandlung von Psoriasis for growth factor epitopes or are argo und or inhibited.

Ferner werden Patienten mit der Wachstumsfaktorzusammensetzung vor dem Beginn oder dem Wiederauftreten nach einer Krebsbehandlung immunisiert.

In addition, patients are immunized with the growth factor composition prior to the start or recurrence after cancer treatment. Accordingly, an object of the present invention to provide methods and compositions for the relief of cancer in a human or animal, or of having cancer. Eine andere Aufgabe der vorliegenden Erfindung ist die Bereitstellung von Verfahren und Zusammensetzungen zur Verhinderung des Auftretens oder einer Ausbreitung von Krebs.

Another object of the present invention is to provide methods and compositions for preventing the occurrence or spread of cancer. Eine weitere Aufgabe der vorliegenden Erfindung ist die Bereitstellung von Verfahren und Zusammensetzungen zur Impfung eines Menschen oder Tiers gegen einen Wachstumsfaktor.

A further object of the present invention is to provide methods and compositions for vaccination of a human or animal against growth factor. Eine weitere Aufgabe der vorliegenden Erfindung ist die Bereitstellung von Verfahren und Zusammensetzungen zur passiven Immunisierung eines Menschen oder Tiers gegen einen Wachstumsfaktor. A further object of the present invention is to provide methods and compositions for passively immunizing a human or animal against growth factor.

Eine weitere Aufgabe der vorliegenden Erfindung ist die Bereitstellung von Wachstumsfaktor enthaltenden Zusammensetzungen, die immunisierend sind und eine Immunantwort gegen einen Wachstumsfaktor bei Menschen oder Tieren hervorrufen. A further object of the present invention is to provide growth factor-containing compositions that are immunogenic and induce an immune response against growth factor in humans or animals. A further object of click to see more present invention is the provision of peptide fragments of a growth factor, which are modified with immunizing units Psoriasis unterscheidet sich von Ekzemen order to increase a response of an individual to a growth factor, and methods of using the same.

Eine weitere Aufgabe der vorliegenden Erfindung ist die Bereitstellung von Peptidfragmenten eines Wachstumsfaktors und modifizierten Peptidfragmenten eines Wachstumsfaktors in Liposomen. A further object of the present invention is the provision of a growth factor peptide fragments and modified growth factor peptide fragments in a liposome.

Eine weitere Aufgabe der vorliegenden Erfindung ist die Bereitstellung von Zusammensetzungen, die ein Peptidfragment eines Wachstumsfaktors enthalten, zusammen mit Adjuvantien, um die Immunantwort zu stimulieren. A further object of the present invention is Bestehende Verfahren zur Behandlung von Psoriasis provide compositions containing a peptide fragment of a growth factor, along with adjuvants to stimulate the immune response.

A further object of the present invention is to provide anti-growth factor antibodies Also Traumeel Salbe für Psoriasis Bewertungen чародей for passively immunizing a human or animal against growth factor. These and other objects, features and advantages of the present invention will become apparent after a review of the following detailed description of the disclosed embodiment and the appended claims.

Detaillierte Beschreibung der vorliegenden Erfindung Detailed description of the present invention. Die vorliegende Bestehende Verfahren zur Behandlung von Psoriasis umfasst Verfahren und Zusammensetzungen zur Vorbeugung oder Linderung von Krebs und Hyperproliferations-Erkrankungen bei einem Mensch oder Tier. The present invention encompasses methods and compositions for the prevention or alleviation of cancer and hyperproliferative diseases in a human just click for source animal.

The compositions immunizing growth factor comprising the present invention include, but are not limited to, growth factor containing carriers, such as liposomes and vesicles, immunizing peptide fragments of a growth factor, immunizing peptide fragments of a growth factor together with adjuvants, modified peptide fragments of a growth factor, modified peptide fragments of a growth factor together with adjuvantsmedia which contain a growth factor peptide fragments, and carriers containing modified growth factor peptide fragments of a contained.

Next, the present invention includes antibodies that are directed against growth factors and specifically for this. Der hier verwendete Ausdruck "Wachstumsfaktor" betrifft polypeptidische Wachstumsfaktoren und polypeptidische Angiogenesefaktoren und modifizierte Derivate und Peptidfragmente derselben.

The term "growth factor" as Web Salbe für Psoriasis der Kopfhaut August herein relates to polypeptidic growth factors and angiogenic factors polypeptidic and modified derivatives and peptide fragments thereof.

A growth factor comprises: The term used here as well, "immunogenic" refers to substances that cause or increase the in Behandlung von Psoriasis of anti-endogenous growth factor antibodies in T-cells and other reactive immune cells and are involved in an immune response in humans or animals.

An individual may have circulating antibodies directed against endogenous growth factors, and yet does not occur immune response of the individual against the growth factor. Therefore, the term as used herein, "nichtimmunisierend" an endogenous growth factor in its native state, which usually causes no, or only minimal amounts of circulating antibodies, T-cells or reactive immune cells, and which normally elicits no immune response in an individual against itself.

An immune response occurs when an individual Schiffe Psoriasis sufficient antibodies, T-cells and other reactive immune cells against administered growth factor compositions of the present invention to mitigate the to be treated cancer or hyperproliferative disease or to alleviate. The term "carrier" as used herein means a membrane structure in which growth factor can be inserted, whereby the growth Es hilft Baby-Creme für Psoriasis or a part of the growth factor on the external surface of the carrier presented or exposed and so that the growth factor-carrier composition reduction immunising against a growth factor will.

Weiter betrifft der Ausdruck "eine effektive Menge" die Menge Wachstumsfaktor, die bei Verabreichung an einen Menschen oder ein Tier eine Immunantwort hervorruft, Krebs vorbeugt, eine Linderung von Krebs bewirkt oder die Ausbreitung und Proliferation von Krebs hemmt.

Next, the Bestehende Verfahren zur Behandlung von Psoriasis "effective amount" means the amount of growth factor that here an immune response when administered to a human or an animal, prevents cancer, causes a relief of cancer or inhibits the spread and proliferation of cancer.

Die effektive Menge wird leicht durch einen Fachmann unter Befolgung von Standardverfahren Lecithin Behandlung von. The effective amount is readily determined by one skilled in the art following standard procedures.

For example, immunogenic growth factor compositions are administered parenterally or orally in a range of cells, was heilt Psoriasis Forum habe 1.

The actual required amount of a growth factor composition for eliciting an immune response will vary for each individual patient depending on the immunogenicity of the administered growth factor composition, and the immune response of the individual. Bestehende Verfahren zur Behandlung von Psoriasis wird die spezifische, an ein Individuum verabreichte Menge durch Routineexperimente und auf Bestehende Verfahren zur Behandlung von Psoriasis Basis des Ausbildungsstandes und der Erfahrung eines Fachmanns bestimmt.

As a result, the specific, administered to an individual amount is determined by routine experimentation and based on the level of training and experience of an expert. The compositions of the present invention Bestehende Verfahren zur Behandlung von Psoriasis growth factor are used for the production of antibodies against parts of a growth factor, which are immunogenic by their presentation in support directed.

Anti-growth factor antibodies are administered to individuals to passively immunize them against growth factor and thereby prevent the initiation of cancer growth, to alleviate existing cancer or Bestehende Verfahren zur Behandlung von Psoriasis the proliferation of cancer. Spa-Behandlung von Psoriasis particular, the present invention comprises a growth factor which is inserted into the membrane carrier so that portions Bestehende Verfahren zur Behandlung von Psoriasis the growth factor will be presented on the carrier surface.

Der Wachstumsfaktor ist normalerweise Bestehende Verfahren zur Behandlung von Psoriasis immunisierend, weil er vom Immunsystem als "selbst" erkannt wird.

The growth factor is normally not immunogenic because it is recognized as "self" by the immune system. However, the insertion of parts of a growth factor into einen Überblick über die Verwendung von Natriumthiosulfat bei Psoriasis surface of liposomes alters the presentation of the growth factor to the immune system, whereby it is immunogenic. Immunizing growth factor-containing liposomes may be made by reconstituting liposomes in the presence of a purified or partially purified growth factor.

Furthermore, peptide fragments can be reconstituted by a growth factor in liposomes. The present invention also includes a growth factor and peptide fragments of a growth factor that has been modified to increase its antigenicity. For example, immunizing units and adjuvants may be linked to the growth factor or Bestehende Verfahren zur Behandlung von Psoriasis with it. Examples of immunizing units and adjuvants include, but are not limited to, Bestehende Verfahren zur Behandlung von Psoriasis muramyl dipeptide derivatives, nonionic block polymers, aluminum hydroxide or aluminum phosphate adjuvant, and mixtures thereof.

The present invention further encompasses growth factor fragments with hydrophobic moieties, such as palmitic acid, modified, which simplifies insertion into the hydrophobic lipid bilayer of a carrier.

Hydrophobic moieties of the present invention may be Bestehende Verfahren zur Behandlung von Psoriasis acids, triglycerides and phospholipids wherein the fatty acid carbon skeleton having at least 10 carbon atoms. Expediently atoms have lipophilic units, the fatty acids with a carbon backbone with at least about 14 carbon atoms and up to about 24 Koh.

Exquisite hydrophobic moieties have a Bestehende Verfahren zur Behandlung von Psoriasis skeleton having at least 14 carbon atoms. Examples of hydrophobic moieties include, but Bestehende Verfahren zur Behandlung von Psoriasis not limited to, palmitic acid, stearic acid, myristic acid, lauric acid, oleic acid, linoleic acid and linolenic acid. Bestehende Verfahren zur Behandlung von Psoriasis preferred hydrophobic moiety is palmitic acid.

Immunizing compositions containing a growth factor, modified growth factor, and peptide fragments thereof, are administered to a human or animal to induce immunity to growth factor.

The immunized human or animal develops circulating antibodies the immunized against growth factor which bind to growth factor, wherein its ability to stimulate cancer cell proliferation is reduced or inactivated. Liposomes with growth factor inserted into the membrane, as well Bestehende Verfahren zur Behandlung von Psoriasis other immunogenic, a growth factor-containing compositions, may also be used to produce a range of monoclonal or polyclonal antibodies, which are specific to a growth factor.

Process for the preparation of antibodies are well known to one skilled in the art. Anti-growth Bestehende Verfahren zur Behandlung von Psoriasis antibodies bind growth factor when administered to individuals, reducing the effective concentration of a growth factor is reduced in the circuit. As a result, a growth factor dependent proliferation of cancer is prevented, reduced or inhibited.

The growth factor-containing compositions and anti-growth factor antibodies are a human or animal by any suitable means, preferably by injection. Beispielsweise wird ein in Liposomen rekonstituierter Wachstumsfaktor durch subkutane Injektion verabreicht. For example, a reconstituted into liposomes growth factor is administered by subcutaneous injection.

Circulating anti-growth factor antibodies bind to the growth factor and reduce or inactivate its ability to stimulate cancer cell proliferation, regardless of whether they are produced internally or supplied from external sources. Liposomes that can be used in the compositions of the present invention include those that are known to one skilled in the art.

Any standard lipids that can be used to prepare liposomes may be used. Standardliposome with double layers and multiple layers can be used for the preparation of compositions of the present invention. Each one skilled in the art known methods for producing liposomes can be used, but preferably the liposomes according to the method of Alving et al.

Das Liposom kann optional ein Adjuvans enthalten. The liposome can optionally contain an adjuvant. Ein bevorzugtes Adjuvans ist ein detoxifiziertes Lipid A, wie Monophosphoryl- oder Diphosphoryl-Lipid A. A preferred adjuvant is a detoxified lipid A, such as monophosphoryl or diphosphoryl lipid A. Wenn die Vesikel Liposome sind, hat der Wachstumsfaktor im Allgemeinen einen hydrophoben Schwanz, der in die Liposommembran bei ihrer Bildung insertiert wird.

When the vesicles are liposomes, the growth factor generally has a hydrophobic tail that is inserted into the liposome membrane during its formation. Furthermore, a growth factor may be modified so that it contains a hydrophobic tail so that the growth factor can be inserted into the liposome. Beispielsweise wird Bestehende Verfahren zur Behandlung von Psoriasis Wachstumsfaktorgen mit einer Oligonucleotidsequenz, die einen hydrophoben Schwanz codiert, fusioniert.

For example, the Wachstumsfaktorgen is a oligonucleotide sequence that encodes a hydrophobic tail fused. Das modifizierte Gen wird unter Verwendung von einem Fachmann bekannten Verfahren in ein Expressionssystem insertiert und in diesem exprimiert, wobei ein Wachstumsfaktorfusionsprotein erhalten wird, das einen hydrophoben Schwanz hat. The modified gene is inserted using a method known to those skilled in an expression system and expressed therein, said a growth factor fusion protein is obtained which has see more hydrophobic tail.

Alternatively, the growth factor on the surface of previously formed liposomes by chemical bond or electro-insertion is exposed.

When the vesicles of a baculovirus-derived vesicles, recombinant growth factor on the membrane of the insect cell is expressed as a natural consequence of processing by the infected insect host cell. As with the embodiment described above with a liposome, a growth factor can be modified so that the recombinantly expressed protein contains a hydrophobic portion to facilitate insertion into the vesicle membrane.

The visit web page is further explained by the following examples, which should still be interpreted in any way as to limit Bestehende Verfahren zur Behandlung von Psoriasis scope thereof. Bestehende Verfahren zur Behandlung von Psoriasis I Example I.

Konstruktion eines Wachstumsfaktor enthaltenden rekombinanten Baculovirus Construction of und Baby Seife growth factor-containing recombinant baculovirus. Das Baculovirus-Expressionssystem wird wie in NR Webb et al. The baculovirus expression system as Bestehende Verfahren zur Behandlung von Psoriasis NR Webb et al.

USA 86, — beschrieben konstruiert. USA 86, describes constructed. A recombinant baculovirus, the cDNA encoding a growth factor with the total length under the transcriptional Bad mit Magnesium Psoriasis of the Polyhedronpromotors contains, is generated by co-transfecting recombinant pAc-growth factor DNA with wild type Autographa californica nuclear polyhedrosis virus AcMNPV DNA by means of a calcium phosphate precipitation produced.

Beispiel II Example II. Expression und Reinigung eines Wachstumsfaktors Expression and purification of a growth factor. Die okklusionsnegativen Viren aus Beispiel I werden aus den Plaques gereinigt und in Bestehende Verfahren zur Behandlung von Psoriasis frugiperda 9 Sf-9 -Zellen propagiert. The okklusionsnegativen viruses from Example I are purified from the plaques and in Spodoptera frugiperda 9 Sf-9 Bestehende Verfahren zur Behandlung von Psoriasis propagated.

Infizierte Sf9-Zellen werden in Monoschichten oder Suspensionen wie in NR Webb et al. Infected Sf9 cells are grown in monolayers or in suspensions such as NR Webb et al. USA 86, — beschrieben propagiert. USA 86, described propagated. Extraction and purification of the recombinantly expressed growth factor is performed by Bestehende Verfahren zur Behandlung von Psoriasis procedures.

Beispiel III Example III. Herstellung von Wachstumsfaktor enthaltenden Liposomen Preparation of growth factor-containing liposomes. Gereinigter Wachstumsfaktor wird durch einem Fachmann bekannte Standardverfahren in Liposome elektroinsertiert Y. Purified growth factor is determined by standard methods known to those skilled in liposomes elektroinsertiert Mouneime Y. Ein Einbau von Wachstumsfaktoren oder Fraktionen derselben in Liposome kann beinhalten: Incorporation of growth factors or Behandlung Genital Psoriasis thereof into liposomes can include: Beispiel IV Example IV.

Herstellung von Wachstumsfaktor enthaltende Baculovirus-Vesikeln Preparation of growth factor-containing vesicles baculovirus. Wachstumsfaktor enthaltende Vesikel werden wie folgt hergestellt. Growth factor-containing vesicles are produced as follows. Von einem Insekt abgeleitete Vesikel, die einen rekombinanten Wachstumsfaktor in ihren Membranen enthalten, werden unter Verwendung einer baculovirusinfizierten Insektenzelle erhalten. By an insect-derived vesicles containing recombinant growth factor in their membranes, a baculovirus-infected insect cell are obtained using.

In particular Spodoptera frugiperda be IPLB-SfAE Klonierungsisolat 9 insect cells designated Sf9 with a recombinant baculovirus containing a gene coding for the overall length of a growth factor cDNA, cultured and infected as described more in Webb et al.

When the cells reach a density of 3. A Vesikelproduktion begins about 24 hours after baculovirus infection. Bestehende Verfahren zur Behandlung von Psoriasis Hauptvesikelbildung is achieved approximately 72 Bestehende Verfahren zur Behandlung von Psoriasis after initial baculovirus infection.

The vesicles have arranged a growth factor on their outer surfaces and can be used for immunization. The vesicles are washed three times with 0. Beispiel V Example V.

Immunisierung mit Wachstumsfaktor enthaltenden Zusammensetzungen Immunization with growth factor-containing compositions. Immunizing growth factor-containing compositions, either liposomes or baculovirus-derived vesicles are a human or animal with a dose of 1 - injected 1, micrograms per kg of body weight.

Titer of antibodies against growth factor are determined by ELISA using the recombinant protein and Meerrettichperoxidasekonjugaten with anti-human or anti-animal immunoglobulins from goat or other serologic techniques sandwich ELISA or evidence of biological activity such as neutralization of natural or synthetic cytokines or growth factor or Kompetitionsnachweise evidence that already exist or have been specifically developed for individual growth factors determined.

Booster injections can be, if needed, administered at levels of protective antibodies sufficient to reduce or neutralize the activity of growth factors in vivo to achieve.

Neutralizing titers and appropriate antibody isotypes are determined in experimental animals by exposure to appropriate cancer cells.

Beispiel VI Example VI. Individuen mit starken Immunsystemen werden wie in Beispiel V beschrieben immunisiert. Individuals with strong immune systems are immunized as described in Example V. After a high titer was obtained of anti-growth factor antibodies, the IgG fraction is isolated from the blood and used as described below for the passive immunization of an individual as described in Example VII.

Beispiel VII Example VII. Passive Immunisierung Passive immunization. Anti-growth factor antibodies isolated from the species that are passive immunization are administered by intravenous injection at a dose amount of about 0. Dose and frequency of administration, in experimental animals, the various types of tumors were exposed, and determines the specific type of tumor and matched to the particular individual to be treated.

Although it may be true that a universal protective standard scheme can be developed, it may also be that effective therapy can be achieved Bestehende Verfahren zur Behandlung von Psoriasis through individual based on the type of tumor criteria.

Although this invention has been described with specific accuracy with reference to the disclosed embodiments, it is understood that many variations and modifications within the scope of the invention as described in the appended claims, can be performed. CAA1DED1EPA1EPA4EPB1USWOA1. HoladayCarol A. BiBTeXEndNoteRefMan.


Bestehende Verfahren zur Behandlung von Psoriasis Best Psoriasis Product Reviews of | julia-kuhn.de

Die Symptome der Psoriasis erfordern eine komplexe Behandlung von Psoriasis Drogen und traditionelle Medizin. Die Studien erwies sich die Wirksamkeit der Behandlung und die Sicherheit der Medikamente Amevive und Raptiva nehmen. Wie zur Behandlung von Http://julia-kuhn.de/krankheit-die-aus-psoriasis-entsteht.php Es wird auf der Grundlage der solidolovoy hergestellt und hat eine gute therapeutische Wirkung.

Im Durchschnitt ist die Behandlung von Psoriasis mit diesem Medikament drei bis Bestehende Verfahren zur Behandlung von Psoriasis Monate. Im Fall der Salbe in der komplexen Therapiebehandlungszeit deutlich reduziert werden kann. Die Wirkstoffe auf die Hautschichten eindringen und wirken auf Nervenrezeptoren, wodurch die Produktion von spezifischen Substanzen, Juckreiz und Brennen Reduzierung, Verringerung der Grad der Symptome.

Es kann nicht nur auf der Haut Bestehende Verfahren zur Behandlung von Psoriasis werden, sondern auch auf der Kopfhaut. Psoriasis - Behandlung und Symptome Wie zur Behandlung von Psoriasis Erkrankungen Der Haut Und Des Subkutanen Gewebes Dermatologie September 10, Behandlung von Haut Psoriasis neueste Behandlung der Krankheit wurde in Amerika vor kurzem von einem Forscherteam entdeckt. Es kann deutlich die sichtbaren Symptome der Psoriasis in relativ kurzer Zeit verringern.

Methodik neuesten Symptome der Psoriasis-Behandlung Kombination von UV-Strahlung mit Medikamenten wie Sandimmun und Tigazon nehmen. Und es Sandimmun bei der Behandlung von schweren Formen der Psoriasis gute Ergebnisse gezeigt. Dieses Verfahren der Behandlung von Psoriasis erfordert nicht die integrierte Nutzung des Photosensibilisators. Verwendung von aromatischen Retinoide in der letzten Behandlung von Psoriasis-Symptome, wie Etretinat http://julia-kuhn.de/psoriasis-behandlung-auf-totem.php Atsetritina.

Hervorragende Ergebnisse werden durch die Verwendung dieser Medikamente in Kombination mit PUVA-Therapie erhalten. Das Medikament ist in der Lage, die Proliferation von Keratinozyten hemmen, um die Geschwindigkeit der Bildung neuer schuppige Bestehende Verfahren zur Behandlung von Psoriasis in Psoriasis zu verringern. Volks Behandlung von Psoriasis 1. Pflanzen Medikamente Beauty Infektionskrankheiten. Colitis ulcerosa Ursachen, Symptome und Behandlung September 27, Eigenschaften und Anwendungen September 27,


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